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Treatment For ADHD The most effective treatment options for add are medications and psychosocial therapy (psychotherapy). The medications include stimulants like methylphenidate, amphetamine, and Atomoxetine. They can also be nonstimulants, like clonidine and Guanfacine. Patients with active substance abuse issues shouldn't take stimulant drugs. However, treatment of add in adults who are in stable remission may look into them. Combination therapy using antidepressants, particularly SSRIs, is an alternative option. Stimulants Stimulants increase dopamine and norepinephrine levels in the brain's synapses. This improves concentration and reduces hyperactivity as well as impulsivity. Most doctors prescribe stimulant medications to treat ADHD. They might prescribe methylphenidate (Concerta, Ritalin) or amphetamines, which are similar medicines. The type of medication prescribed will depend on the person's individual biochemistry and how well they react to the medicine. It could take anywhere from five to seven days before the full effects of the medication become visible. Improvements in concentration, improved memory, better sleep and less impulse control are all indications that the medication is working. Medications in this class can cause side effects, such as diminished appetite and trouble sleeping, and they may increase blood pressure and heart rate. Certain people with a medical condition such as high blood pressure or heart disease, should not use these medications. They are controlled substances with a potential for abuse. Only psychiatrists or pediatricians or in certain cases general practitioners, may prescribe stimulants. They are available in the form of pills, tablets, patches that go on the skin or liquids. Children and adolescents who are dependent on stimulants are often affected by weight loss and a lack of appetite. They can also develop tics when the dose is too high. In this situation, the doctor will reduce the dose to prevent the drug from worsening symptoms. About 70-80 percent of adults and children with ADHD are treated with stimulant drugs. The majority of children and young people notice that their symptoms improve when they receive treatment. This is particularly relevant for children who have parents, teachers, or caregivers who have reported improvements. Early use of stimulants can lower the risk of developing substance use disorders later on in life. Wilens Katusic, Wilens colleagues81,82, and Biederman, et al83, found that stimulant therapy reduces the risk of developing substance use disorders during the adolescent years. However this protective effect fades by early adulthood.